Craighead County is a county located in the U.S. state of Arkansas. As of the 2000 census, the population was 82,148. The 2007 Census estimate shows the county increasing to 92,640 people. It is included in the Jonesboro, Arkansas Metropolitan Statistical Area.

Craighead County is Arkansas's 58th county, formed on February 19, 1859, and named for state Senator Thomas Craighead. The county has two county seats — Jonesboro and Lake City. It is one of several dry counties within the state of Arkansas,

in which the sale of alcoholic beverages is largely prohibited. Craighead County was part of the territory claimed by France on April 9, 1682 by René Robert Cavelier, Sieur de La Salle who laid claim to all of the land drained by the Mississippi River and its assorted tributaries. LaSalle's claim was named Louisiana in honor of Louis XIV, King of France.